Molecular Formula | C42H64O14 |
Molar Mass | 792.96 |
Density | 1.27 |
Melting Point | 117-119°C |
Boling Point | 821.8±65.0 °C(Predicted) |
Specific Rotation(α) | 0 (c, 0.032 in MeOH) |
Solubility | Soluble in methanol, acetone, DMSO, insoluble in petroleum ether and other solvents. |
Appearance | Colorless needle crystal |
pKa | 12.89±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD22417326 |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the customs vine. |
Reference Show more | 1. Li Siyu Zhang lunar November Han Li Zhang Hui. Simultaneous determination of three saponins in Vine from 22 producing areas by HPLC-DAD-ELSD method [J]. Chinese patent medicine 2019 41(05):1144-1146. 2. Yan Min, Li Jun, Song Yuelin, et al. Characterization of chemical profile of clearance Vine using HPLC-IT-TOF-MS [J]. Chinese herbal medicine 2018 49(21):106-115. |
introduction | customs Marsdenia ten acissima(Roxb.)Wight et Arn. MarsdeniaR. Brown is a plant of the genus Roxaceae (Asclepiadaceae), also known as Tongguang Vine, Tongguang San, Black Bone Vine and Lower Milk Vine. Customs clearance vine is rich in C21 steroid derivatives (mainly C21 steroid glycosides) and polysaccharides, but also contains a small amount of alkaloids and resins, among which C21 steroid glycosides are the material basis of anti-inflammatory, anti-tumor and anti-fertility activities of customs clearance vine. Gitanin G is one of its effective active ingredients. |
biological activity | Tenacissoside G is a C21 steroid from the stem of Marsdenia tenacissima. Tenacissoside G reverses multidrug resistance in multidrug-resistant cancer cells overexpressed by P-glycoprotein (Pgp). |
chemical properties | soluble in methanol, ethanol, DMSO and other organic solvents, derived from customs vines. |